FDA approves drug which helps to slow progression of rare form of MND

Title: FDA Approval of New Drug Offers Hope for Treatment of Rare Form of MND


Motor Neuron Disease (MND) is a challenging and debilitating condition that affects over 6,000 people in the United States every year. Recently, the FDA has approved a new drug that can help slow the progression of a rare form of MND, offering hope for those living with this devastating disease. In this blog post, we will explore the key points surrounding the FDA’s approval of this new drug and what it means for the future of MND treatment.

Key Points:

  1. Understanding Motor Neuron Disease:
    Motor Neuron Disease is a group of progressive neurological disorders that attack the motor neurons, which are responsible for transmitting nerve signals to the muscles. As these neurons die, the muscles weaken and atrophy, causing problems with movement, speech, and breathing. There is currently no cure for MND, and the available treatments provide only limited relief.
  2. The Rare Form of MND:
    Amyotrophic lateral sclerosis (ALS) is the most common form of MND, but there are several other types, including primary lateral sclerosis (PLS). PLS is a rare type of MND that progresses slowly and primarily affects the upper motor neurons. Symptoms include muscle stiffness and weakness in the legs, along with difficulty with fine motor movements such as writing and buttoning clothes.
  3. New Drug for Slow Progression of PLS:
    In a significant development, the FDA has approved a new drug called Riluzole oral film (brand name Exservan) for the treatment of PLS. Riluzole is a glutamate inhibitor that has been shown to slow the progression of the disease, thereby delaying the need for respiratory support or wheelchair use. The drug is the first-ever oral film for PLS treatment and is expected to improve patients’ quality of life significantly.
  4. Positive Results from Clinical Trials:
    Clinical trials of Riluzole oral film have had positive results, demonstrating that the drug can slow disease progression by up to 20%. In addition, the oral film formulation makes the drug easier to administer and more convenient for patients, thereby improving compliance and adherence.
  5. Hope for MND Patients:
    The FDA’s approval of Riluzole oral film offers hope for not only patients with PLS but also those living with other forms of MND. The drug represents a significant advancement in the treatment of MND, highlighting a new approach to managing the condition and provides optimism in the development of future treatments.
  6. Advancing Research in MND Treatment:
    The approval of Riluzole oral film also signals progress in research and development of new treatments for MND. Currently, research is ongoing to identify additional drugs and other therapeutic interventions that may help improve the symptoms and early diagnosis of the disease.


The FDA’s approval of Riluzole oral film is a significant development in the treatment of MND, specifically PLS. With a new approach to treatment, patients can benefit from this transformative medication, previously unavailable to them. The drug offers hope for people living with MND, contributing to efforts to improve their quality of life and prognosis. We can expect further advancements in the management of MND in the future, with the approval of this groundbreaking drug driving research and development for future advancements in treatment.